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2x higher than Core, adjustable up to 1000mg with $50 per additional 100mg ) Ascorbic Acid 40005000mg (22.5x higher than Core) Alpha Lipoic Acid (ALA) 100150mg (23x higher than Core) Glutathione 10001500mg (up to 2x higher than Core) Methylcobalamin (B12) 5mg (post-infusion push) Mini: 6090 min Plus: 24 hrs Max: 36 hrs NAD tiers take longer because NAD is infused slowly for comfort/tolerance

GFP and RFP expressions were detected by FACS assay

FIGURE 2 3 Common models for research on blue light damage to eye diseases 3.1 Summary of cell modeling conditions The replication of disease models through ex vivo cells has the advantages of short experimental time, convenient operation, easy observation, good controllability, and reduced use of experimental animals

(B) Heat map presenting the 41 metabolites found in the four treatment groups

Indications: To produce miosis (reduction of size) of the iris in seconds after delivery to the lens in cataract surgery, and in other types of eye surgery where rapid miosis is required (e.g